KMID : 0882420060710060600
|
|
Korean Journal of Medicine 2006 Volume.71 No. 6 p.600 ~ p.608
|
|
Histological comparison of endoscopic forceps biopsy with endoscopic mucosal resection in the gastric lesions.
|
|
Kim Jee-Yeon
Lee See-Won Park Lee-Chun Shin Jung-Kwang Park Nam-Young Moon Won Kim Kyu-Jong Park Moo-In Park Seun-Ja Chang Hee-Kyung
|
|
Abstract
|
|
|
Background: The correct histological diagnosis of a gastric adenoma is important, because an adenoma has been reported to be a precancerous lesion and is associated with focal gastric carcinoma. However, there is some discrepancy between the histology of a forceps biopsy and that of the endoscopic mucosal resection. This study compared the histological findings of a gastric mucosal lesion in the specimens of a forceps biopsy and an endoscopic mucosal resection.
Methods: 88 cases of gastric mucosal lesions, which had been removed by the endoscopic mucosal resection, were reviewed retrospectively. All the patients had undergone a forceps biopsy before the endoscopic mucosal resection. The histological findings of the specimens by a forceps biopsy were compared with those by resection.
Results: The histological findings were accordant at 52 of the 88 cases (59.1%). Among the 71 cases with adenoma or gastritis in the biopsied specimens, 13 cases (18.3%) were finally diagnosed with gastric cancer in the resected specimens. Among all the gastritis and adenomas determined by the forceps biopsy, the high-risk groups for adenocarcinomas were characterized by the following endoscopic findings: red-colored and depressed lesions.
Conclusion: Biopsy specimens may not be representative of the entire lesion. Therefore, an endoscopic resection of a gastric mucosal lesion is needed for making an accurate histological diagnosis and treatment if adenomas such as red-colored or depressed lesions are suspected.
|
|
KEYWORD
|
|
Gastric mucosal disease, Forceps biopsy, Endoscopic mucosal resection, Histolgy
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|